What the work involves

You are writing the exam, not taking it. Each task starts from a realistic biostatistics problem — an interim analysis with a protocol deviation, a propensity-score matched cohort with unmeasured confounding, a non-inferiority margin that doesn't hold up, a statistical analysis plan section that an agency reviewer would push back on. You source or construct the supporting materials (synthetic or de-identified trial data, protocol excerpts, patient-level records, SAP or CSR sections), define the methodologically correct solution path, and then decompose that solution into a rubric of 35 or more discrete, checkable items covering both methodological rigor and clinical interpretation.

The rubric is where most of the effort lands. It needs to separate a defensible analysis from a plausible-sounding wrong one: did the model handle the missing-data mechanism appropriately, choose an estimand consistent with the question, adjust for multiplicity, avoid over-reading a secondary endpoint. Tasks that read like textbook exercises get rejected — the brief explicitly asks for the messiness of real practice.

What the screen looks for

  • Verifiable depth: specific trials, therapeutic areas, study designs, and regulatory contexts you have personally worked in, not general familiarity.
  • Methodological judgment under follow-up: expect the interviewer to challenge your chosen approach and see whether you can defend it or revise it cleanly.
  • Rubric thinking: can you articulate what distinguishes a correct answer from a subtly wrong one, in terms someone else could grade against.
  • Tooling: working command of R, SAS, Python, or Stata applied to actual clinical or epidemiological data.
  • Honest availability: minimum weekly task submissions apply, and starts are fast.

Logistics

Fully remote, contractor engagement, asynchronous. Compensation is per accepted task rather than hourly, so effective rate depends on how efficiently you work — the $60–100/hr band reflects what experts have reported, not a guarantee. micro1 typically fills these roles within about 48 hours and expects first tasks within 24–48 hours of onboarding. Most contributors treat this as part-time alongside existing work, but the weekly minimum is real and worth confirming before you accept.